3D computational model of mechanism of human ocular accommodation

Session Details

Session Title: Multifocal IOLs and Advanced Optic

Session Date/Time: Tuesday 08/09/2015 | 09:00-10:30

Paper Time: 09:45

Venue: Main Auditorium

First Author: : A.Hipsley USA

Co Author(s): :    S. Salinas Blemker   S. Chen   B. Bao   D. Goldberg           

Abstract Details

Purpose:

To develop a 3D finite element computational model of the normal functioning accommodation mechanism in the eye which includes the lens, the zonular fibers, the ciliary body/muscle, and the sclera in order to illuminate the mechanical function of accommodation, specifically the function of the ciliary muscles.

Setting:

University of Virginia Biomedical Engineering Department Research Study, Virginia.

Methods:

A literature review of data on accommodation function are used to define the geometry and material properties of the anatomical structures. Available biometry and imaging data is incorporated. 3D Computational modeling and Finite Element Analysis (FEA) of the mechanism of accommodation was developed. Nike3D ,FEBio, and AMPS software is used. Model predictions of lens accommodation were compared with the literature and clinical knowledge. Analysis of ciliary muscle specific effects on the accommodation mechanism are demonstrated.

Results:

The 3D Computational model was able to demonstrate the strain forces of the ciliary muscle during accommodation and disaccommodation in our lab. We were able to demonstrate force vectors toward the lens both agonistic and antagonistic. The model was validated with published experimental measurements and demonstrated statistically significant utility for predicting lens accommodation and central optical power as a result of ciliary body contraction.

Conclusions:

Integration of accommodation mechanisms imaging and computer models may prove a valuable tool to reveal structure-function relationships and improve presbyopia surgery outcomes. New insights are needed to improve technology and treatment of both emmetropic presbyopia and cataract surgery that also have a presbyopic application such as accommodating IOLS.

Financial Interest:

One of the authors receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, One of the authors travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, One of the authors research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented