Combined eye-gel containing sodium hyaluronate and xanthan gum for the treatment of corneal epithelium defect after pterygium surgery

Session Details

Session Title: Cornea - Medical

Session Date/Time: Monday 07/09/2015 | 08:00-10:30

Paper Time: 09:00

Venue: Room 17

First Author: : T.Kocaturk TURKEY

Co Author(s): :    A. Gencgonul   F. Balica   M. Ozbagcivan   H. Cakmak           

Abstract Details

Purpose:

To compare the effectiveness of the ophthalmic gels containing hyaluronate, xanthan gum and netilmycine with fusidic acid in terms of corneal epithelium recovery periods in the patients who underwent pytergium surgery.

Setting:

Adnan Menderes University Faculty of Medicine,Department of Ophthalmology,Aydin,Turkey

Methods:

Patients who underwent pytergium surgery were separated into two groups. 40 patients in Group 1 were given eye gel containing sodium hyaluronate, xanthan gum and netilmycine and 40 patients in Group 2 were given one drop of eye gel containing fucidic acid. The patients in both groups were examined on the 12nd, 24th and 48th hours in the postoperative period by using slit-lamp technic. The recovery periods of the corneal epithelium defect and the subjective complaints of the patients such as pain, stinging, were also monitored comparatively fluorescein strip staining.

Results:

The mean ages were 26±8 and 24±6 in Group 1 and 2, respectively. The closure period of the corneal epithelium defect was observed as 24±8 and 36±12 hours in Group 1 and 2, respectively. The number of the patients suffering from subjective complaints such as pain and stinging in the first 12 hours was 6 in Group 1 and 29 in Group 2. The difference was significant both clinically and statistically (p=0.001).

Conclusions:

Combined eye gel containing hyaluronate, xanthan gum and netilmycine accelerates the recovery of corneal epithelial defect and reduce the complaints of the patients when compared with the fusidic acid gel. Combined eye gel should be considered as an option for the treatment of the corneal epithelium defect related with pytergium surgery.

Financial Interest:

NONE