Clinical validation of an optical instrument to measure straylight in cataract patients

Session Details

Session Title: Corneal Astigmatism Assessment. Surgery Equipment

Session Date/Time: Saturday 05/09/2015 | 11:00-13:00

Paper Time: 12:34

Venue: Main Auditorium

First Author: : H.Ginis GREECE

Co Author(s): :    A. Pennos   L. Hervella   B. Canizares   M. Ruiz Sanchez   J. Marin   P. Artal     

Abstract Details

Purpose:

A compact instrument based on the optical integration method (Sigma straylight-meter) has been developed and adapted for fast clinical measurements of intraocular scattering. We validated the instrument in a clinical setting in terms of its sensitivity in the detection and classification of cataracts.

Setting:

Hospital Universitario Virgen de la Arrixaca and Laboratorio de Optica, University of Murcia

Methods:

Cataract patients (N=51, Age=62.3 ±10,6 years) free of other known ophthalmic pathology were randomly recruited at the University hospital. The protocol included slit lamp examination and photography, manifest refraction, straylight measurement with laboratory prototype of the optical instrument (Sigma) and psychophysical (functional) assessment of straylight with C-Quant (C-Quant, Oculus GmbH, Wetzlar, Germany). Slit lamp photographs of the crystalline lens were utilized to classify cataract severity using the Lens Opacities Classification System III (LOCS III)

Results:

The logarithm of the straylight parameter for the Sigma measurements ranged from 0.79 to 2.09 (Mean: 1.34) while the psychophysical values ranged from 0.67 to 1.82 (Mean: 1.22). The Pearson correlation coefficient for significance level 0.01 “2-tailed” for the two sets of measurement is r=0.665 for the psychophysical compared to the optical method. The straylight values of different LOCSIII grades differed significantly from each other.

Conclusions:

The Sigma straylight optical instrument is capable of measuring accurately the amount of intraocular scattering in a clinical setting and classifying cataracts precisely in an objective manner. This may be a step towards the comprehensive evaluation of the cataract eye's optics in clinical settings.

Financial Interest:

NONE