Posters
In-vitro assessment of a novel intraocular lens made of crosslinked polyisobutylene (xPIB) material
Poster Details
First Author: G.Auffarth GERMANY
Co Author(s): G. Labuz L. Zhang H. Fang S. Schickhardt I. Lieberwirth D. Munro
Abstract Details
Purpose:
To describe and analyse the optical and material quality of a new intraocular lens (IOL) made of a unique crosslinked polyisobutylene (xPIB) material: recording the labelled power and modulation transfer function (MTF) of a sampled IOL and assess surface quality using scanning electron microscopy (SEM): to confirm it is manufactured to the published manufacturing norms, standards and tolerances; and to confirm that it is labelled correctly by the manufacturer.
Setting:
The David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany
Methods:
The EyeDeal® Lens is made from crosslinked polyisobutylene (xPIB) – which is a new polymer in IOL manufacture. The lens is now at a pre-clinical stage of laboratory assessment. We assessed the material quality using an accelerated ageing process (to provoke glistenings) and compared values with a control, AcrySof® lens. Images of the lens surface were recorded with scanning electron microscopy (SEM). Optical quality was assessed by measuring the labelled power and MTF using standard metrology equipment.
Results:
The EyeDeal® had an average glistening density result of 7.46±3.78 MV/mm2 compared to the control Acrysof® whose glistenings number was 142.42±72.47mv/mm2. Using SEM, EyeDeal® lenses were examined in the optic-centre; optic-edge, haptics and haptic-optic junction, all appeared to be comparable to modern IOLs made of acrylic materials. In particular, the central area of the optic was smooth and cleanly finished. The power and MTF values were normal and conformed to ISO standards.
Conclusions:
These are encouraging results for a lens that is not made of hydrophobic- or hydrophilic-acrylic. In the laboratory, the EyeDeal® lens showed equivalence to current acrylic lens models. Indeed, it showed superiority in its glistening density result compared to the control lens. This allows for cautious optimism that it will succeed in implantation studies in animals and eventually do well in human clinical trials.
Financial Disclosure:
research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented
