Posters

Isopure IOL: optical principles and first clinical outcomes of a new EDOF monofocal intraocular lens

Poster Details

First Author: Z.Halasova CZECH REPUBLIC

Co Author(s):    P. Stodulka   M. Slovak                 

Abstract Details

Purpose:

The purpose of this prospective clinical data collection is to investigate first clinical outcomes after bilateral implantation of ISOPURE intraocular lenses (IOLs), manufactured by PhysIOL, Liége, Belgium. This enhanced monofocal intraocular lens allows patients to experience high-quality vision at far distances and improved useful vision at intermediate distances.

Setting:

Gemini Eye Clinic, Zlin, Czech Republic

Methods:

In this ongoing surgeon initiated clinical data collection, 19 patients (37 eyes) have been implanted with ISOPURE lens as part of cataract surgery. Follow-up examinations included: uncorrected Visual Acuity (UDVA), corrected distance Visual Acuity (CDVA), uncorrected (UIVA) and distance-corrected intermediate Visual Acuity (DCIVA) at 66cm and 80cm. Distance-corrected and cylindrical defocus curves were recorded between -2.5D and +1.5D in 0.5 D steps, except for ±0.25 D in order to test for intermediate behaviour of the IOL. Contrast sensitivity was performed under mesopic and photopic conditions.

Results:

The interim results on 37 eyes at 1 month and 28 eyes at 6 months postoperative show mean refractive outcomes (MRSE) 0.26±0.41D and -0.21±0.55D respectively. Mean Distance Corrected Visual Acuity CDVA, DCIVA (66cm), DCIVA (80cm) in logMAR are -0.03±0.04 0.27±0.17, 0.21±0.15, respectively at 1 month and -0.06±0.05, 0.29±0.13, 0.20±0.10, respectively at 6 month (28 eyes). Mean Uncorrected Visual Acuity values for UDVA, UIVA (66cm), UIVA (80cm) in logMAR are 0.09±0.14, 0.20±0.21, 0.19±0.14, respectively at 1 month and 0.09±0.17, 0.28±0.17, 0.20±0.11, respectively at 6 months. Defocus curve follows the expected course for an EDOF lens. Contrast Sensitivity curve follows the expected course.

Conclusions:

Preliminary results after implantation of ISOPURE show very good restoration of visual functions for far and intermediate distances. This is an important step for an expansion of the monofocal IOL category, as today most monofocal lenses only correct for far distances and thus do not improve the intermediate vision that is required for many daily tasks. Larger studies with longer follow up are needed to prove the optical concept of this new IOL and confirm the expected reduction of photic effects compared to multifocal IOLs. In the presentation, the outcomes of a longer follow up will be presented.

Financial Disclosure:

research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented