Posters

Anterior segment surgical procedures influence on TBUT

Poster Details

First Author: M.Radenkovic SERBIA

Co Author(s):    M. Vasovic    M. Petrovic   G. Stankovic Babic   J. Djordjevic Jocic   M. Trenkic   A. Veselinovic     

Abstract Details

Purpose:

Surgical approach to the anterior segment disrupts tear film. Symptoms of Ocular Surface Disease occur after cataract, glaucoma, refractive, corneal, vitreoretinal surgery. Pathomechanism of occurrence depends on the procedure: cutting of corneal nerves, conjunctival lesions that decrease number of goblet cells, mucin distribution change or chronic inflammation. As initial therapy artificial tears are essential because tear volume increase, mucus adhesion, reduction of tear osmolarity, evaporation and three layer tear film maintainance.

Setting:

Aim of this study that was conducted in Eye Clinic of Clinical Center was to examine tear break-up time (TBUT) in patients after different surgical interventions (cataract surgery-Extra Capsular Extraction (ECCE), pterygium, glaucoma surgery) and monitoring tear film recovery with / without the use of artificial tears.

Methods:

Retrospective-prospective study included: 105 eyes with OAG (POAG / XFG) after trabeculectomy, 20 eyes after ECCE, 12 after pterygium surgery with various artificial tears. They were divided into 6 groups: 60 glaucoma did not use artificial tears (group 1), 12 used hyaluronic acid (HA) tears (group 2), 24 glaucoma patients carboxymethyl-cellulose (group 3), 9 glaucoma HA/trehalose (group 4), 20 ECCE (group 5 ) and 11 pterygium use (group 6) used HA/trehalose. Obtained TBUT results at follow-up interval (preoperatively, day 7, 30, 60) statistically processed by SPSS18.

Results:

Gender distribution was not significantly diferent in groups male(52.94%) vs female(47.06%). Reduced TBUT (<10s) preoperatively found in all glaucoma patients at different percentage in groups (44.44-62.50%). Cataract patients were the oldest and highly reduced TBUT (<10s) in 55% and 9.09% in operated pterygium. On the seventh postoperative day, TBUT was reduced in 73.3%- 95% in all groups, mostly after ECCE and trabeculectomy group with CMC (95%), followed by the fastest TBUT improvement for 15% (to 80%) in the HA/trehalose group (ECCE/glaucoma) but after 60 days drop use improvement of TBUT(>10s) was present in HA/trehalose group (55%).

Conclusions:

TBUT parameter analyzes and determines the postoperative difference among groups with/ without artificial tears. The results of this clinical screening indicate the importance of early recognition, faster recovery, and prompt tear use which improves quality of life and tear film integrity.

Financial Disclosure:

None