Posters

Outcomes of cataract surgery in eyes with pseudoexfoliation syndrome

Poster Details

First Author: A.Ong UK

Co Author(s):    Z. Shalchi                    

Abstract Details

Purpose:

To compare the outcomes of phacoemulsification in eyes with and without pseudoexfoliation syndrome.

Setting:

District general hospital in England (Prince Charles Eye Unit, Windsor)

Methods:

We included all eyes hat underwent phacoemulsification between March 2009 to October 2019. Eyes were classified as pseudoexfoliation or no pseudoexfoliation based on pre-operative examination findings. Eyes with a history of ocular trauma or intraocular surgeries known to cause an increased risk of complications were excluded. The independent t-test and chi-squared test were used to compare continuous and categorical variables respectively. The significance level was set at 5%.

Results:

Eyes in the pseudoexfoliation group (n=209) tended to have worse pre-operative logMAR visual acuity (VA) (mean±SD, 0.83±0.62 vs 0.71±0.53, p=0.001), were older (79.4±7.0 vs 75.3±10.0, p<0.001), and required the use of a capsular tension ring (0.9% vs 3.3%, p<0.001) than the non-pseudoexfoliation group (n=26,834). The rate of posterior capsule rupture, iris trauma, and dropped lens, and corneal oedema were comparable between the groups, but the incidence of zonular dialysis was higher in the pseudoexfoliation group (2.9% vs 0.5%, p<0.001). With regard to postoperative complications, the pseudoexfoliation group had a significantly higher incidence of corneal oedema (12.4% vs 5.8%, p<0.001) and postoperative uveitis (3.8% vs 1.6%, p=0.032). Although fewer pseudoexfoliation eyes achieved a final VA of 0.3 or better (65.1% vs 71.4%, p=0.045), both groups had a comparable improvement in LogMAR VA at 1 month (-0.46 ± 0.736 vs -0.414 ± 0.583, p=0.253).

Conclusions:

Eyes with pseudoexfoliation have a higher risk of some intraoperative (zonular dialysis) and postoperative complications (corneal oedema and post-operative uveitis). Despite this, both groups experienced comparable improvements in VA following cataract surgery.

Financial Disclosure:

None