Posters

Evaluation of continuous intraocular lenses transparency using rabbit experimental model

Poster Details

First Author: H.Matsushima JAPAN

Co Author(s):    M. Nagata   K. Mukai   T. Senoo              

Abstract Details

Purpose:

Glistening and sub-surface nano glistenigs (SSNG) are well known as opacifications of intraocular lenses (IOLs) after cataract surgeries. However, it is difficult to analysis it in eyes. In this study, the opacifications were evaluated using rabbit eyes.

Setting:

Department of Ophthalmology, Dokkyo Medical University, Tochigi, Japan.

Methods:

Eyes of 8 weeks albino rabbits had phacoemulsification after that, 5 types of IOLs (SN60WF before changing production process by Alcon (Q code), SN60WF after changing (A code), ZCB00 Johnson and Johnson, YP2.2 Kowa, XY1 HOYA) were implanted. After 6 months post operation, the IOLs were extracted and cleaned. The IOLs were placed in model eye maintaining a constant temperature. The surface and inner light scatterings of the IOLs were imaged and analyzed with an anterior segment analyzer (NIDEK). The intensity of light scattering was quantified in a selected area of surface or inner of IOL using densitometry.

Results:

The ZCB00V, YP2.2 and XY1 developed a few glistening but no SSNG. However; the Q code developed glistening and mild SSNGs. The A code developed same levels of glistening but SSNGs were decreased.

Conclusions:

The long periods implantation in rabbits are useful experiment to evaluate glistening and SSNG in hydrophobic acrylic IOLs. The resent IOLs are designed to prevent water phase separations.

Financial Disclosure:

research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented