Posters

Scanning electron microscopic features of degraded hydrophobic acrylic intraocular lenses which were explanted after being in vivo for a prolonged period

Poster Details

First Author: M.Garg INDIA

Co Author(s):    H. Bhattacharjee   S. Buragohain   H. Javeri   I. Agarwalla   B. Gokani   A. Ahir     

Abstract Details

Purpose:

To study and document glistening in explanted hydrophobic microvacuoles affected acrylic intra-ocular lenses which were in vivo for an average duration of 11 years by electron microscopic evaluation.

Setting:

Sri Sankaradeva Nethralaya (a tertiary care eye hospital), Guwahati, Assam, India.

Methods:

Scanning electron microscopic (SEM; Hitachi S 3000 N EXAX Genesis VP SEM) study of five explanted hydrophobic acrylic intraocular lenses (IOL) which had clinically evident microvacuoles prior to explantation. The IOLs were in vivo for a prolonged period and needed explantation for various indications. Only those hydrophobic acrylic IOLs which fulfilled the inclusion criteria were included. The findings were compared with control specimens.

Results:

The IOLs were in vivo for an average duration of 11.6 years. The cause of explantation of IOL was subluxation in 4 cases and low visual acuity in one case. Bulk degradation and microvacuoles on cut sections throughout the IOL optics and undulating surface patterns over both the surfaces of the IOL has been documented in all the specimens. No such findings were noted in the control specimens where the surface and texture was homogenous.

Conclusions:

SEM findings of the structural changes in explanted IOL documented in the study demonstrates that hydrophobic acrylic IOL are degradable in vivo. Microvacuoles are a clinical manifestation of the structural changes that occur at a microscopic and molecular level. These changes are not seen in IOLs which have not undergone intraocular implantation. To our knowledge, a similar study of this kind has not been done.

Financial Disclosure:

None