Posters
Intrasession repeatability of pupillometric measurements under different light levels obtained with a multidiagnostic device in healthy eyes
Poster Details
First Author: D.Pinero Llorens SPAIN
Co Author(s): D. de Fez I. Cabezos A. López-Navarro M. Caballero V. Camps H. Fukumitsu
Abstract Details
Purpose:
To evaluate the intrasession repeatability of pupillometric measurements provided by a multidiagnostic platform in a large sample of healthy eyes.
Setting:
University Clinic. Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain
Methods:
Prospective study enrolling a total of 100 healthy eyes of 100 patients with ages ranging from 23 to 65 years old. Repeated pupillometric measures under photopic (P, 220 lux), mesopic (M, 160 lux), low mesopic (L, 70 lux), and scotopic conditions (S, 1 lux) with the VX120 system (Visionix-Luneau Technologies, Chartres, France) were obtained after a complete eye exam. Likewise, the measurement of pupil size was done once in the fellow eye in a total of 75 eyes. The level of intrasession variability as well as differences between fellow eyes were evaluated.
Results:
Most of differences between repeated measures did not exceed 0.5 mm (from 82% for S to 100% for P). No significant differences between repeated measures were found for S (p=0.099) and L (p=0.751). However, statistically significant differences were found for M (p=0.002) and P (p=0.003). The analysis of clinical relevance of differences between pairs (Passing-Bablok) only confirmed the clinical relevance of differences between the first and second repeated measurement of M. Concerning the comparative analysis between fellow eyes, no statistically significant differences in pupil size were found between right and left eyes in any light condition evaluated (p≥0.227).
Conclusions:
The VX120 system can provide consistent measurements of pupil size under scotopic, low mesopic and photopic conditions, with a relative limitation under mesopic conditions.
Financial Disclosure:
None
