Posters
Anterior chamber flare levels following iStent inject trabecular micro-bypass surgery
Poster Details
First Author: L.Danieliute UK
Co Author(s): A. Amon A. Nagar A. Daas I. Rodrigues S. Goyal K. Lim
Abstract Details
Purpose:
Post-operative inflammation results from disruption of the blood-ocular barrier. There is limited literature on ocular inflammatory response following minimally invasive glaucoma surgery. This prospective study aims to assess the effect of stand-alone iStent inject trabecular micro-bypass surgery on ocular inflammation in pseudophakic eyes.
Setting:
The study took place at Ophthalmology Department, St Thomas' Hospital, London, UK.
Methods:
Consecutive patients undergoing stand-alone iStent inject trabecular micro-bypass surgery were followed up for three months. Post-operative steroid regime included G. Dexamethasone 0.1% four times a day for one month. Aqueous flare was measured using KOWA FM-600 laser flare meter prior to surgery, at one week, one month and three months after the surgery. An average of 8 readings were performed at each visit with the highest and lowest readings discarded.
Results:
11 pseudophakic patients undergoing iStent inject trabecular micro-bypass surgery were included. Mean age was 68.5 years, there were 7 African/Black Caribbean, 2 Asian and 2 White patients. Ten patients had primary open angle glaucoma and one patient had ocular hypertension. At baseline, mean flare was 13.7±3.7 photons/millisecond. The flare rate peaked at 26.5±5.0 (p=0.04) photons/millisecond one week post-surgery. At one month and three months post-operatively, flare readings returned close to baseline: 17.7±4.0 (p=0.19) and 16.3±6.6 (p=0.26) photons/millisecond respectively. There were no complications of surgery observed.
Conclusions:
Our results demonstrate that anterior chamber inflammation returns to baseline levels as early as one month after stand-alone iStent inject trabecular micro-bypass surgery in pseudophakic eyes.
Financial Disclosure:
None
