Posters

The protective effects of diquafosol eyedrops after femtosecond laser-assisted cataract surgery

Poster Details

First Author: K.Yamazaki JAPAN

Co Author(s):    R. Kimoto   Y. Shibata   J. Yoneyama   T. Hayashi   T. Mimura        

Abstract Details

Purpose:

To prospectively analyze the protective effects of diquafosol eyedrops on the ocular surface following femtosecond laser-assisted cataract surgery (FLACS)

Setting:

Omiya Nanasato Eye Institute, Saitama, Japan

Methods:

Bilateral FLACS with trifocal IOL (PanOptix) implantation was performed in 24 patients (13 males, 11 females, average age 68.9 ± 6.4 years old). Patients received 3% diquafosol eyedrops 6 times daily in the right eye (diquafosol group), and physiological saline 6 times a day in the left eye (saline group). Other medication included 1.5% levofloxacin, 0.1% dexamethasone and 0.1% diclofenac 3 times daily in both eyes. Pre and postoperative tear break-up time (BUT), superficial punctate keratopathy (SPK) scores, visual function were compared between both eyes, and all patients answered the Dry Eye Related Quality of Life Score (DEQS) questionnaire.

Results:

BUT between groups were similar preoperatively and on first day post-op, however, BUT was statistically longer in the diquafosol group compared to saline at 1 week (5.5/3.8 secs) and 2 weeks (4.8/3.1 secs) (p<0.05). There was no difference in SPK score, best corrected distance visual acuity, tear meniscus height, contrast sensitivity, DEQS and Schirmer test at all time points. Spherical aberration was statistically lower in the diquafosol group at 1 week. The protective effects of diquafosol on BUT was more pronounced in patients with pre-operative BUT less than 5 seconds compared with those with BUT longer than 6 seconds.

Conclusions:

Diquafosol eyedrops prevented the shortening of BUT following FLACS, especially in patients with short preoperative BUT values.

Financial Disclosure:

None