Posters

Comparison of changes in corneal endothelial cell density and central corneal thickness between conventional and femtosecond laser-assisted cataract surgery: a prospective randomized trial with 6 months of follow-up

Poster Details

First Author: E.Chlastatwardzik POLAND

Co Author(s):    A. Nowińska   E. Wylęgała                 

Abstract Details

Purpose:

The purpose of the study was to compare the changes of corneal endothelial cell density and central corneal thickness after femtosecond laser-assisted cataract surgery versus micro-incision cataract surgery versus small-incision cataract surgery.

Setting:

Chair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland

Methods:

This is a randomized, prospective case-control clinical trial. 87 patients undergoing phacoemulsification surgery were included in the study.Patients were randomly selected into three groups: FLACS, MICS(1.8mm) and SICS(2.4mm) group. Pre- and postoperative data were evaluated by anterior segment optical coherence tomography and non-contact specular microscopy. Criteria for inclusion in the study and exclusion from the study in selected groups of patients are identical. Control examinations were performed preoperatively and at postoperative day 1, week 1, month 3 and 6. Corneal endothelial cell density and central corneal thickness were analyzed. The endothelial cell density changes and its percentage lost were calculated.

Results:

The ECL% was statistically significant lower in the FLACS group on the 7th day, 1 month and 6-months postoperatively (p<0.05). The CCT was statistically significant lower in the FLACS group and in the MICS group than in the SICS group on the 7th postoperative day (p=0.002). However, in the 6 months follow-up there was no statistically significant difference in the CCT between studied groups (p=0.133). To conclude in the 6 months follow-up CCT was comparable between studied groups. There was statistically significant difference found between eyes undergoing FLACS, MICS and SICS with respect to percentage endothelial cell density lost.

Conclusions:

To conclude in the 6 months follow-up there was statistically significant difference found between eyes undergoing FLACS, MICS and SICS with respect ECL%. Postoperative CCT was comparable between studied groups during the 6 months’ follow-up period.

Financial Disclosure:

None