Posters

Streptococcus oralis/mitis corneal infections: a case series

Poster Details

First Author: N.Lorenzana Blanco SPAIN

Co Author(s):    N. Alejandre Alba                    

Abstract Details

Purpose:

Streptococcus oralis/mitis are commensal bacteria of the oral cavity that belongs to the Streptococcus viridans group capable of forming biofilms that make them resistant to host defense mechanisms and antibiotic therapy leading to chronic and recurrent infections. The purpose of this study is to report the clinical evolution of patients with corneal ulcers and infiltrates in relation to these microorganisms and its proper management.

Setting:

Fundación Jiménez Díaz University Hospital, Madrid, Spain.

Methods:

All patients with Streptococcus oralis/mitis corneal ulcers treated at our centre until January 2020 were included. Follow-up was performed recording visual acuity, symptoms, slit-lamp examination, photographic imaging and anterior segment optical coherence tomographies.

Results:

Two patients, 47 and 85 aged women, were included. First case was a lens wearer with a history of myopic laser in situ keratomileusis, trachoma conjunctivitis and recurrent keratitis and corneal erosions episodes. Second patient had a history of recalcitrant keratitis in both eyes, failed dacryoscitorrinostomy surgery 3 years earlier and a recent infectious corneal infiltrate due to pseudomonas aeruginosa with suspected perforation that required urgent penetrating kertatoplasty and suffered subsequent superinfection by streptococcus oralis/mitis. Both patients presented torpid course with poor response to antibiotic and surgical treatment until full thickness corneal transplants were performed, thus eliminating all biofilm.

Conclusions:

Biofilm infections usually fail to be completely eliminated, produce recurrent episodes and most of the time must be resolved by replacing the implant or living tissue affected as exclusively antibiotherapy is not enough.

Financial Disclosure:

None