Posters

Comparison between corneal biomechanics and HbA1c levels in healthy individuals and type 2 diabetic patients

Poster Details

First Author: S.Mandour EGYPT

Co Author(s):    H. Elmazar   M. El Bahnasy   .               

Abstract Details

Purpose:

The aim of this study was to evaluate the corneal biomechanical properties using the ocular response analyzer (ORA) in type 2 diabetic patients.

Setting:

A total of 150 eyes of 75 patients were enrolled in a cross-sectional prospective comparative study from May 2015 to May 2016. Patients were selected from ophthalmology outpatient clinics in Giza Research Institute for Ophthalmic Researches.

Methods:

Patients were divided into three equal groups. Group A: included 50 eyes of age-matched normal individuals. Group B: included 50 eyes of patients having diabetes mellitus type 2 with HbA1c less than 7. Group C: included 50 eyes of patients having diabetes mellitus type 2 with HbA1c greater than 7. ORA and HbA1c evaluation were carried out for all patients.

Results:

Corneal hysteresis ranged from 5.5 to 9.8 mmHg for the control group (group A), and from 6.00 to 11.4 mmHg for group B, whereas it ranged from 9.5 to 15.20 in group C. The corneal resistance factor of the study groups ranged from 5.8 to 10.00 mmHg for the control group (group A), from 6.2 to 12.00 mmHg for group B, and from 8.90 to 16.10 mmHg for group C.

Conclusions:

Corneal Biomechanics in diabetic groups are significantly higher compared with those of the control group. Morever, corneal bimechanics are higher in uncontrolled disbetes. This should be considered in diabetic patients who will have any corneal procedure whether diagnostic or therapeutic.

Financial Disclosure:

None