Posters

Clinical outcomes of Descemet's membrane endothelial keratoplasty in eyes with toxic anterior segment syndrome

Poster Details

First Author: N.Gunaydın TURKEY

Co Author(s):    N. Tutas Gunaydin   B. Kandemir   B. Tanyildiz              

Abstract Details

Purpose:

To evaluate the feasibility and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) in eyes with toxic anterior segment syndrome (TASS) after cataract surgery.

Setting:

Department of Ophthalmology, Dr. Lutfi Kırdar Kartal Traning and Research Hospital, tertiary referral center, Istanbul, Turkey. Turkey.

Methods:

In this retrospective, interventional case series the clinical outcomes of 10 DMEK procedures for endothelial decompensation due to TASS were analyzed. Main outcome measures were best-corrected visual acuity (BCVA), endothelial cell density(ECD), central corneal thickness (CCT) and postoperative complications.

Results:

Mean follow-up time was 21± 4 months. Mean preoperative BCVA was logMAR 2.1 and improved to logMAR 0.67 at 1 year postoperatively. The mean ECD was 2456 ± 197.76 cells/mm2 preoperatively and 1098 ± 217.6 cells/mm2 at 12th months (p=.008). The mean CCT of the patients was 735.42 ± 68.9 preoperatively and 598.28 ± 84.42 months at 12th month (p = .005). The rebubbling rate was 30% (11/24). Secondary glaucoma in 3 eyes (30%) was controlled by medical treatment and Re-DMEK was performed in 3 eyes (30%) who developed graft failure.

Conclusions:

Our data provide evidence that DMEK is feasible for the treatment of endothelial decompensation in eyes with TASS.

Financial Disclosure:

None