Posters

The use of OmniLenz in treating persistent corneal epithelial defects

Poster Details

First Author: M.Elalfy UK

Co Author(s):    S. Maqsood   K. Elsawwah   N. Dhillon   S. Hamada   D. Lake        

Abstract Details

Purpose:

Amniotic membrane (amnion) is the thin avascular inner layer of the foetal membrane. When appropriately preserved, the favourable effects of promoting wound healing, reducing inflammation and neovascularisation can be conserved to promote restoration of healthy tissue. This study aims to report the outcomes of using Human amniotic membrane derived dry matrix with a contact lens (OmniLenz) in the management of persistent corneal epithelial defects (PEDs) of various aetiologies.

Setting:

Queen Victoria Hospital and Maidstone Hospital, UK

Methods:

A retrospective study of 86 eyes with PED between Oct 2017- Nov 2019 at two centres in the UK, all treated with Human amniotic membrane derived dry matrix. Data collection included patients’ demographics, PED aetiology and duration, concomitant treatments, time to healing and best corrected visual acuity before and after application of OmniLenz were recorded

Results:

Ninety- three defects of 86 patients (60 males, 33 females) age range 7 to 92 years were treated Omnilenz. Ten eyes required more than one application of OmniLenz during the course of their disease. Fifty-eight percent of the eyes showed complete healing, and 28% showed partial decrease of the size of persistent epithelial defects. Only 14% of eyes showed worsening of visual acuity

Conclusions:

OmniLenz is easily applied in the clinical setting for eyes with PED. Its transparency allows for easy visualization and examination of the cornea. Its use has demonstrated the safety and efficacy of a new tool available to treat persistent epithelial defects

Financial Disclosure:

None