Posters

Autologous serum for the treatment of grade 2 and 3 neurotrophic keratitis: 2 years follow-up

Poster Details

First Author: S.Bagaglia ITALY

Co Author(s):    S. Zuccarini   A. Crisà   F. Puce              

Abstract Details

Purpose:

To evaluate management of Iatrogenic Neurotrophic keratitis with autologous serum treatment in 34 patients affected by, iatrogenic NK

Setting:

University of Siena, Departement Of Opthalmology , Siena Italy Villa Donatello Private Hospital Florence Italy

Methods:

34 patients (19 female, 16 males) with diagnosis of secondary Neurotrophic Keratitis ( NK) were enrolled, (mean age: 72,1 ± 11Y) Patients were treated with autologous serum for 1 year. Patients where included in 3 groups according to recent NK classifications (stage I, II,III ). Confocal microscopy evaluation (IVCM), anterior segment (AS.OCT) Minimum corneal thickness MCT , and Best corrected visual acuity where performed at 15 days, 1 month 3 months 6 months and 12 months after treatment.

Results:

All 36 patients showed a good to complete recovery of corneal Neurotrophic keratitis starting form 1 month after the beginning of treatment, BCVA increased from a baseline 0,395 avg logMAR to 0,24 logMAR at 12th month ,remaining stabile up to the 24th month MCT increased from 356 average μm at baseline to 465 average μm at the end of follow up remaining stabile at the and of the follow up 24 months

Conclusions:

According to literature and to our brief study results, autologous serum is a valid medical approach for the treatment of Neurotrophic keratitis

Financial Disclosure:

None