Posters

Histopathologic finding in cornea of sulfur mustard exposed patients 30 years after exposure

Poster Details

First Author: H.Aghamollaei IRAN

Co Author(s):    K. Jadidi   S. Daryabari   F. Asadi Amoli              

Abstract Details

Purpose:

Delayed mustard gas keratopathy (DMGK) is the main chronic outcome in eye chemical injured patients The aim of this study was histopathological evaluation of mustard exposed cornea after more than 30 years.

Setting:

Baqiyatallah University of Medical Sciences

Methods:

Twelve corneas after Lamellar keratoplasty was evaluated in this study. Corneal tissue were prepared by histologic methods and stained by H&E.

Results:

The main histopathological findings in these cases were presence of severe stromal edema and corneal scar. In the sections with visible superficial epithelium ,Subepithelial bullae formation ( Bullous keratopathy ) was seen. Focal or diffuse disruption of Bowman membrane and replacement with fibrosis were also seen .There was no evidence of stromal vascularization and inflammation in all specimens.

Conclusions:

After more than 30 years, extensive corneal scar is seen in sulfur mustard exposed patients. Scar tissue without vascularization and fibroblastic proliferation is the main finding in sulfur mustard exposed cornea. This pathology results is different from other scars.

Financial Disclosure:

None