Posters
Pseudophakic negative dysphotopsia and intraocular lens orientation: a prospective double-masked randomised controlled trial
Poster Details
First Author: G.Manasseh UK
Co Author(s): G. Manasseh E. Pritchard A. Rothwell J. Luck
Abstract Details
Purpose:
To determine whether horizontal orientation of the intraocular lens optic-haptic junctions has an effect on the incidence of pseudophakic negative dysphotopsia.
Setting:
A surgical Ophthalmology Unit within a National Health Service (NHS) general hospital in Bath, UK.
Methods:
Single-centre prospective double-masked randomised controlled trial. 220 eyes of 201 participants undergoing routine cataract surgery were randomised to receive their intraocular lens either orientated with the optic-haptic junctions at 180degrees (“horizontal”) or without manipulation following implantation (control). Patients were excluded according to age (19-99 years), co-existing eye disease affecting visual function and insufficient cognition to complete the study. In the fourth post-operative week a telephone interview was conducted to determine rates of negative dysphotopsia. The data were analysed to provide the relative risk of negative dysphotopsia with horizontal orientation of the IOL optic-haptic junctions compared with standard treatment.
Results:
Orientating the IOL optic-haptic junctions horizontally halved the incidence of pseudophakic negative dysphotopsia in the fourth post-operative week (9/110 in the intervention group; 18/110 in the control group) (RR 0.50, 95% CI 0.235 to 1.064, p=0.072). The overall incidence of negative dysphotopsia was 12.2% (27/220 participating eyes). No intraoperative adverse effects of intraocular lens rotation were reported.
Conclusions:
The simple intraoperative manoeuvre of rotating the intraocular lens to orientate the optic-haptic junctions at 180 degrees may be a safe and effective measure to reduce the risk of developing post-operative pseudophakic negative dysphotopsia in the first post-operative month.
Financial Disclosure:
None
