Posters

Effectiveness of pulmonary surfactant in the treatment of corneal edema

Poster Details

First Author: T.Artuc TURKEY

Co Author(s):    M. Batur                    

Abstract Details

Purpose:

To compare the effectiveness of topical surfactant and 3% sodium chloride in the treatment of corneal edema occurring after cataract surgery.

Setting:

This prospective study was conducted in Van Yuzuncu Yil University Faculty of Medicine, Department of Ophthalmology.

Methods:

Ninety eyes of 90 patients with no corneal disease who underwent cataract surgery were included in the study. Thirty eyes without corneal edema comprised group 1. Patients with corneal edema were divided into two groups: those treated with 3% sodium chloride (group 2, 30 eyes) and those treated with surfactant drop (group 3, 30 eyes). All patients underwent central corneal thickness (CCT) measurement with anterior segment optical coherence tomography and endothelial cell count (ECC) measurement with non-contact specular microscopy before surgery and at postoperative 1, 7, and 14 days.

Results:

The mean age was 70.8±6.6 years, with no significant age difference between the groups. Preoperatively, there was no significant difference in mean CCT or mean ECC among the groups(p=0.999). On postoperative day 1, CCT was significantly lower in group 1 (p<0.001) but did not differ between groups 2-3(p=0.999). There was no significant difference between groups in terms of ECC(p>0.05). At postoperative day 7 and 14, CCT differed significantly between groups 1-2(p<0.001) and between groups 2-3(p=0.001), with no significant difference between groups 1-3(p=0.474). ECC was significantly higher in group 1(p<0.05), while there was no significant difference between groups 2-3(p>0.05).

Conclusions:

According to our literature search, this study is the first use of pulmonary surfactant for an ocular pathology. Surfactant may be a more effective treatment option than hypertonic sodium chloride for the treatment of corneal edema that develops after cataract surgery.

Financial Disclosure:

None