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Six-months follow-up of changes in corneal densitometry after transform allograft corneal inlay for presbyopia

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First Author: S.Hacıagaoglu TURKEY

Co Author(s):    C. Tanriverdi   A. Ozpinar   A. Kilic              

Abstract Details

Purpose:

To determine and compare the changes in corneal density after transform allograft corneal inlay for presbyopia.

Setting:

Istanbul Medipol University School of Medicine, Ophthalmology Department, Istanbul, Turkey

Methods:

This case series included fourty-seven eyes of 47 patients with a follow-up of 6 months. Corneal lenticules with a refractive target add power of 2.5 D (Transform, Allotex Inc. Boston,USA) is implanted in the non-dominant eyes. Anterior (120µ) layer over the annular diameters for Zone 1: 0.0 mm to 2.0 mm and Zone 2: from 2.0 mm to 6.0 mm corneal density (Version 1.20r36) were evaluated with Scheimpflug tomography (Pentacam, Oculus, Wetzlar, Germany) at baseline and postoperative 1, 3 and 6 months of follow-up. Values were statistically compared with Repeated-Measures ANOVA test and post hoc test analyzed with Bonferroni test.

Results:

The mean baseline densitometry values were 19.30 ± 1.69 for Zone 1 and 17.67 ± 1.32 for Zone 2. Densitometry values increased significantly at 1st month (to Zone 1: 23.53 ± 2.63, p<0.001 and Zone 2: 19.13 ± 1.72, p<0.001). Density values peaked at 3 month follow-up (to Zone 1: 24.34 ± 3.79, p<0.001 and Zone 2: 19.31 ± 2.10, p<0.001). Between the 3 months and 6 months follow-up periode the density values decreased significantly back to baseline resulting in an insignificant change to pre-operative values. By 6 months densitometry values (Zone 1: 19.77 ± 2.89, p=1.000 and Zone 2: 16.81 ± 2.37, p=0.176).

Conclusions:

Transform allograft corneal inlay for presbyopia induce transient increase in corneal densitometry measurement increasing within the first 3 postoperative months and returning back to baseline at 6 months follow-up periode. Measured increase was found to be comparable to other corneal procedures reported in the literature.

Financial Disclosure:

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