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Effect of atropina on the progression of myopia: pilot study

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First Author: M.Canto Cerdan SPAIN

Co Author(s):    A. Amesty-Morello   R. Diez-De-la-Uz   A. Siverio-Colomina   P. Yebana   J. Alio        

Abstract Details

Purpose:

The aim of this study is to analyze the increase in axial length and its relationship with the increase in myopia in patients treated with atropine 0.01%.

Setting:

Vissum Miranza, Alicante, Spain

Methods:

Retrospective, observational and longitudinal study conducted in two groups of myopic patients between the ages of 6 and 16. A control group was compared with a group of patients treated with 0.01% atropine, instilling one drop a day every night. The time interval between each visit was one year. Visual acuity values are collected without and with correction and subjective refraction. To measure the progression of myopia, the measurement of axial length (AL) and average corneal curvature (Km) was obtained using the IOL Master 500 (Zeiss) optical biometer.

Results:

110 eyes were analyzed (control group n=60, mean age 10.46±3.26 years; atropine group n=50, mean age 10.12±3.98 years). At comparison of the annual increase in EE and LA there were statistically significant differences (p <0.05) between the control group (EE: -0.44±0.37D; LA: 0.22±0,15mm) and the atropine group (EE: -0.36±0.45D; LA: 0.15±0.16mm) but not in Km. In the control group, the EE increased by 19% annually and the LA showed an annual increase of 1.5%, while in the group treated with atropine the EE increased 6% annually and the LA showed an annual increase of 1.4%.

Conclusions:

There is a minor increase in axial length and spherical equivalent in patients treated with atropine 0.01% and there are no changes in keratometry values.

Financial Disclosure:

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