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IBERIA Biobank: causes of explantation– phakic and pseudophakic IOLs

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First Author: K.Mena Guevara SPAIN

Co Author(s):    A. Rodriguez   J. Murta   R. Barraquer   L. Bataille   J. Alio        

Abstract Details

Purpose:

The main objective of this work is to present the explant causes of the different intraocular lenses existing in the ophthalmic market, phakic and pseudophakic IOLs, collected in the IBERIA Biobank of ophthalmic explants until 2020.

Setting:

1. Division of Ophthalmology, Miguel Hernandez University, Alicante, Spain. 2. VISSUM Miranza, Alicante, Spain. 3. Department of Ophthalmology, Coimbra University, Coimbra, Portugal. 4. Barraquer Ophthalmology center, Barcelona, Spain. 5. Ocular Diopter Node, OFTARED - RETICS, Spain.

Methods:

The explanted IOLs are stored in a fixation solution to preserve biological information. RETICS members collect the explanted material from the eye along with the related data and send it to IBERIA Biobank, where they register and store it for future studies. The development and expansion of the IBERIA Biobank is one of the milestones in the current RETIC project with reference number RD16/0008. The group headed by Professor J.L. Alio has published two thesis, nine papers and nine conference contributions based on the Biobank data.

Results:

Nowadays, the IBERIA Biobank gathers a total of 1402 IOLs. In fact, of the total amount recorded 45% are phakic lenses and 55% are pseudophakic lenses. Focusing on phakic lenses, the main causes of explant are: lens opacity (42,63%), endothelial damage (6,73%) and lens exchange (4,17%). Similarly, in pseudophakic lenses, the main causes of explant are: lens subluxation (24,42%), bilensectomy (cataract surgery with explantation of a PIOL) (10,28%), keratoplasty (7,46%), lens opacity (5,40%) and multifocal IOL neuroadaptive failure (4,37%). In both types of lenses, phakic and pseudophakic, the rest of the causes include minimum percentages.

Conclusions:

To increase the quality of life of patients, it is necessary to carry out a collaborative work, to further deepen the causes of explant of these biomedical devices. The IBERIA Biobank is available for the scientific community. These data are available on request and with the agreement of the specific committee for research studies. All interested centers can contribute and broaden the Biobank by sending the explanted samples with the form. If you have any questions or your institution is interested in collaborating, please contact the IBERIA Biobank Director, Dr. Alió, (jl.alio@umh.es) or the IBERIA Biobank (biobanco.iberia@umh.es).

Financial Disclosure:

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