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Handheld anterior segment optical coherence tomography in secondary childhood glaucoma

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First Author: D.Elfayoumi EGYPT

Co Author(s):    D. El-Fayoumi   Y. El Sayed   G. Gawdat   -. -           

Abstract Details

Purpose:

This study describes the anterior chamber angle (ACA) structures in infants and children with secondary congenital glaucoma.

Setting:

The study was done in the Pediatric eye hospital, Cairo University.

Methods:

This is a cross-sectional descriptive study that included 30 eyes diagnosed with secondary congenital glaucoma. Ten eyes were diagnosed as Peters anomaly, 6 eyes were diagnosed as aniridia, 8 eyes were diagnosed as Axenfeld-Reiger anaomaly, 3 eyes diagnosed as secondary glaucoma to Sturge-Weber syndrome, one eye diagnosed as glaucoma associated with neurofibromatosis type 1. Two eyes were post-traumatic. We used hand-held anterior segment optical coherence tomography (HH-ASOCT) OPTOVUE IVUE SD-OCT.

Results:

The study included 30 eyes with secondary congenital glaucoma in children aged below 5 years. In Peters anomaly, corneal imaging using the AS-OCT confirmed the diagnosis. It showed malformed posterior stromal corneal fibers and malformed interrupted Descemet’s membrane. In Axenfeld-Reiger anomaly, we were able to confirm the diagnosis through imaging posterior embryotoxon, iris strands adherent to the Schwalbe line, iris hypoplasia, and maldeveloped (fetal) ACA. In aniridia, all eyes had an iris stump, the trabecular meshwork and ciliary processes were visible posterior to the stump. In phacomatoses, also the anomalous ACA was clearly identified.

Conclusions:

Using HH-ASOCT permits thorough examination of the ACA in infants and children with secondary congenital glaucoma and helps in understanding the pathophysiology of the disease as well as the choice of the proper surgical technique.

Financial Disclosure:

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