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Effect of tropicamide and phenylephrine on astigmatism axis and its implications in corneal marking
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First Author: C.Rocha de Lossada SPAIN
Co Author(s): J. Sánchez-González F. Zamorano-Martín R. Rachwani-Anil M. García-Lorente D. Flikier S. Nebro-Cobos
Abstract Details
Purpose:
To analyze astigmatism power and axis changes after tropicamide and phenylephrine combined instillation.
Setting:
1)Regional University Hospital of Malaga (Malaga, Spain), (2) Ophthalmology Clinic Dr. Nebro (Malaga, Spain) and (3) Ocular Surgery Institute (San José, Costa Rica).
Methods:
108 eyes from fifty-four patients enrolled this prospective, cross-sectional study. Before tropicamide and phenylephrine dilation an exhaustive ocular test was achieved. Power and axis value from flat, curve and mean keratometry were extracted from auto kera-refractometer. In a second test, topography and tomography pattern were measured with the Pentacam HR® single rotation Scheimpflug camera. Subsequently, tropicamide 1% (Alcon Cusí, Barcelona, Spain) and phenylephrine hydrochloride 10% (Alcon Cusí, Barcelona, Spain) were instilled twice, with a five minutes time difference between each instillation. The quantity instilled was a drop in each eye. After thirty minutes, the AKR and Pentacam tests were repeated.
Results:
Mean flat and steep counterclockwise axis change was 3.94 ± 5.76 and 3.48 ± 7.64 degrees, respectively (P < 0.01). More than 10 degrees in 15.0% and 13.55% for flat and steep meridian. Mean flat and steep clockwise axis change was 4.38 ± 6.02 and 4.58 ± 7.53 degrees, respectively (P < 0.01). More than 10 degrees in 10.00% and 10.30% for flat and steep meridian, respectively.
Conclusions:
Astigmatism axis significantly change after tropicamide and phenylephrine dilation. Eye marking prior to a toric intraocular lens implantation or astigmatism corneal refractive surgery should be done under the same dilatation terms in which astigmatism has been quantified
Financial Disclosure:
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