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The effect of body mass index, smoking, diabetes and hypertension on corneal endothelium cells before and after cataract surgery

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First Author: K.Mohamed-Noriega MEXICO

Co Author(s):    B. Campos-Casas   A. Martínez-Martínez   A. Quiroga-Garza   R. Elizondo-Omaña   S. Guzmán-López   J. Mohamed-Hamsho     

Abstract Details

Purpose:

To describe the role of body mass index (BMI), smoking, diabetes and hypertension in corneal endothelial cell density (ECD), percentage of regular hexagonal cells (HEX) and coefficient of variation (CV) before and after cataract surgery

Setting:

Single Center, Ophthalmology Department from the University Hospital of the Autonomous University of Nuevo Leon, in Monterrey, Mexico.

Methods:

Prospective consecutive study of all patients listed for cataract surgery between May 2018 and December 2019. All patients underwent corneal endothelial specular microscopy before cataract surgery and one month post operatively. Corneal morphometric values (ECD, CV, HEX) were compared between groups: patients with diabetes, hypertension, smoking and overweight/obesity with their control groups.

Results:

We included 679 eyes; mean age was 66±12 years; male gender was 38.0% (259) and female 61.9% (420). Mean pre-operative and post operative ECD was 2405.51 ± 450 cells/mm2 and 2132.31 ± 507 cells/mm2 respectively. No significant differences were found in the pre or post surgical endothelial values between genders or ages. No significant differences were found in ECD, CV or HEX pre or post surgery between patients with normal BMI, overweight or obesity, nor a higher percentage of endothelial loss. No significant differences were found in smoking or hypertensive patients either.

Conclusions:

Diabetes, smoking, hypertension, BMI and ICC do not represent a lower ECD in patients who attend cataract surgery, nor do they predispose to a greater loss of post-surgical ECD.

Financial Disclosure:

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