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Use of hyaluronidase in peribulbar block: a randomised, double masked comparison to study the incidence of post surgical ptosis

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First Author: A.Gandhi INDIA

Co Author(s):    R. Aggarwal   L. Sarkar                 

Abstract Details

Purpose:

To study the effect of hyaluronic acid used in peribulbar anaesthesia on the incidence of post cataract ptosis. The use of hyaluronidase can alter the effects of local anesthetic; it acts to increase the spread of anesthetic between tissue planes by action of hyaluronic acid. No study has previously directly evaluated the effects of hyaluronidase with respect to the incidence of postoperative ptosis.

Setting:

Safdarjung hopsital, New Delhi, India over a period of one and a half year

Methods:

A total of 200 eyes of 200 patients fulfilling the inclusion and exclusion criteria were enrolled in this randomized, double masked study and underwent phacoemulsification with PCIOL implantation by the same surgeon. Patients were divided into group A(who recieved peribulbar block containing hyaluronidase) and group B (peribulbar block without hyaluronidase) and evaluation of marginal reflex distance, vertical fissure height was done preoperatively and 1st day, 3rd day, 1week, 1 month, and 3 months post operatively quantitavely and photographically. Data was analysed in SPSS. P value <0.05 was considered significant.

Results:

There was a significant difference in the incidence of post cataract ptosis in group A patients as compared to group B (p=0.02)

Conclusions:

The use of hyaluronidase can alter the effects of local anaesthetic and increase the incidence of post cataract ptosis.

Financial Disclosure:

None