Posters

Corneal imaging and densitometry measurements in juvenile keratoconus patients to monitor disease progression and treatment outcomes after corneal cross-linking

Poster Details

First Author: K. Alzahrani UK

Co Author(s): F. Carley   A. Brahma   S. Biswas   Y. Lin   D. Morley   M. Hillarby     

Abstract Details

Purpose:

In this study densitometry software for the Oculus Pentacam been used to investigate the treatment outcomes of CXL in juvenile keratoconus patients before and after receiving treatment up to one year and compare it with a same age match healthy eyes.

Setting:

Manchester Royal Eye Hospital

Methods:

A retrospective comparative study was carried out at Manchester Royal Eye Hospital. Corneal densitometry measurements collected before and after CLX treatment for 9 eyes from KC patients were analysed and compared to corneal densitometry of 40 eyes from healthy volunteers. The compression was including different corneal layers and zones.

Results:

Analysis of densitometry measurements found higher corneal densitometry after CLX which reach the highest level at three months post treatment. There was significant diversity in corneal densitometry measurements at full thickness in the area of (0-2 mm, 2-6mm and 0-10mm) between control, pre-treatment and post-treatment in 3,6,12 months (p ˂0.05). Significant differences found between pre-treatment and post-treatment at three, six and twelve months at full thickness of 0-2 mm and 2-6 mm area zone (p ˂0. 05). However, no significant difference found between pre and post treatment, at full thickness zone of 6-10mm and 0-10 mm.

Conclusions:

Corneal zone of 0-2 mm and 2-6 mm found to be the most affected area of treatment. Corneal haze seems to reach its maximum level at three months after treatment. Level of corneal haze appears to be improved at six months’ time before it is picked up again at one year. Oculus Pentacam provides an objective evaluation to monitor the cornea status after the treatment.

Financial Disclosure:

None