Posters

Optical coherence tomography angiography of optic disc perfusion in glaucoma cases

Poster Details

First Author: R. Diaz Cespedes SPAIN

Co Author(s): A. Hervas   S. Garcia Delpech   E. Sanz   P. Udaondo   D. Salom        

Abstract Details

Purpose:

To compare optic disc perfusion between normal subjects and subjects with glaucoma using optical coherence tomography (OCT) angiography and to detect optic disc perfusion changes in glaucoma.

Setting:

The study was done at AIKEN, Valencia

Methods:

One eye of each subject was scanned by a high-speed 1050-nm-wavelength swept-source OCT instrument. The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was used to compute 3-dimensional optic disc angiography. A disc flow index was computed from 4 registered scans. Confocal scanning laser ophthalmoscopy (cSLO) was used to measure disc rim area, and stereo photography was used to evaluate cup/disc (C/D) ratios. Wide-field OCT scans over the discs were used to measure retinal nerve fiber layer (NFL) thickness.

Results:

n normal discs, a dense microvascular network was visible on OCT angiography. This network was visibly attenuated in subjects with glaucoma. The intra-visit repeatability, inter-visit reproducibility, and normal population variability of the optic disc flow index were 1.2%, 4.2%, and 5.0% CV, respectively. The disc flow index was reduced by 25% in the glaucoma group (P = 0.003). Sensitivity and specificity were both 100% using an optimized cutoff.

Conclusions:

Optical coherence tomography angiography, repeatably measures optic disc perfusion and may be useful in the evaluation of glaucoma and glaucoma progression.

Financial Disclosure:

None