Posters

The efficacy of microperimetry and contrast sensitivity testing in the diagnosis of chiasmal compression caused by pituitary adenomas

Poster Details

First Author: M. Sarnat-Kucharczyk POLAND

Co Author(s): E. Mrukwa-Kominek                    

Abstract Details

Purpose:

The aim of the study is to determine the parameters in microperimetry and contrast sensitivity testing, which are the most useful in the diagnosis of chiasmal compression caused by pituitary adenomas.

Setting:

Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland

Methods:

Patients with macroadenoma of pituitary gland were divided into two groups depending on the absence (group 1) or presence (group 2) of optic chiasm compression detected in magnetic resonance imaging (MRI) with contrast. Each of the study groups and control group included 20 patients (40 eyes). Altogether 60 patients (120 eyes ) were examined.

Results:

Analysis of the variables between control group and group 1 showed no statistically significant differences in mean sensitivity (MS) and mean defect (MD) in microperimetry. Only after division of the examined area in microperimetry into quadrants, the difference has been demonstrated in mean sensitivity in lower-nasal quadrant (MS LN) and mean defect in lower-nasal quadrant (MD LN) between those groups. The analysis of receiver operating characteristic (ROC) curves indicated that parameters such as MS LN in microperimetry, row D and E in contrast sensitivity could be highly specific to predict early optic nerve damage in patients with pituitary adenoma.

Conclusions:

Microperimetry and contrast sensitivity testing are non-invasive diagnostic examinations additional to MRI, which enable detection of optic chiasm compression due to pituitary adenomas and are useful for monitoring disease progression.

Financial Disclosure:

None