Posters

Topography-guided photorefractive keratectomy with accelerated corneal collagen cross-linking (KXL) in mild to moderate keratoconus

Poster Details

First Author: K. Chopra INDIA

Co Author(s): V. Bhandari   S. Ganesh                 

Abstract Details

Purpose:

To evaluate the results of simultaneous topography guided photorefractive keratectomy (PRK) with accelerated corneal collagen crosslinking (KXL) in the management of mild to moderate keratoconus

Setting:

Cornea And Refractive Department, Nethradhama Superspeciality Eye Hospital, Bangalore, India.

Methods:

In this prospective, interventional study, 16 patients (24 eyes) with mild to moderate keratoconus and pachymetry more than 400 microns were treated with Topography guided PRK with the Mel-90 Excimer LASER (Carl Zeiss Meditec AG, Jena, Germany; wavelength 193nm) with accelerated corneal collagen crosslinking KXL(Avedro KXL, Waltham, MA, USA) with the use of riboflavin and ultraviolet A irradiation. Patients were followed up for six months. Topographic parameters, visual acuity and endothelial cell count were monitored. Pre- and post-operative parameters were compared.

Results:

Preoperative mean Specular Endothelial Count was 2620 +/- 156 cells/mm2 which decreased to 2529 +/- 107 cells/mm2 at six months post operative follow up. Preoperative mean (logMAR) uncorrected visual acuity was 0.49 +/- 0.28 and best spectacle-corrected visual acuity was 0.18 +/- 0.1, which improved postoperatively to 0.28 +/-0.29 (p< 0.05) and 0.08 +/- 0.08 (p<0.05), respectively. The mean steepest keratometry was reduced from 45.4 +/- 3.7 D preoperatively to 43.2+/- 2.9D at six months follow-up.

Conclusions:

Simultaneous topography guided photorefractive keratectomy (PRK) with accelerated corneal collagen crosslinking (KXL) is a promising treatment which can provide functional vision in patients with mild to moderate keratoconus.

Financial Disclosure:

None