Update on the comparison of femtosecond laser-assisted lens surgery to conventional cataract surgery: a systematic review and meta-analysis

Session Details

Session Title: Cataract
Session Date/Time: Saturday 11/02/2017 | 08:30-11:00
Paper Time: 08:36
Venue: Auditorium 1

First Author: T. Kohnen GERMANY
Co Author(s): L. Mathys  K. Petermann  E. Herrmann  W. Mayer  M. Shajari     

Abstract Details

Purpose:

This systematic review and meta-analysis compares femtosecond laser cataract surgery (FLACS) with conventional cataract surgery (CCS) and reviews prospective and retrospective clinical trials.

Setting:

Frankfurt University

Methods:

We systematically searched the peer-reviewed literature in Medline (30.04.2015 ﾖ 25.09.2016), Cochrane Library (13.05.2015 ﾖ 25.09.2016) and Embase (13.07.2015 ﾖ 25.09.2016) according to PRISMA guidelines. Only prospective and retrospective trials, which performed FLACS as well as CCS and compared both procedures, were included. The effect measures were risk differences or standardized mean differences. A total of 42 studies (35 prospective, 7 retrospective) with a total of 9,400 eyes undergone FLACS and 8,779 eyes undergone CCS were included.

Results:

No significant difference was found assessing clinically manifested macular edema (P=0.88), incidences of elevated intraocular pressure within 24 hours after surgery (P=0.79), corrected distance visual acuity (CDVA) after 6 months or more (P=0.07) and posterior capsule rupture (P=0.41). In eyes treated with FLACS CDVA after 1 week (P<0.01) and uncorrected distance visual acuity (UDVA) at last visit (P=0.05) were better, endothelial cell loss was less (P<0.01), capsulotomy circularity was better (P<0.01) risk for anterior capsule rupture higher (P<0.01), corneal thickness one day after procedure (P<0.01) less when compared with those undergoing CCS.

Conclusions:

FLACS has a similar complication profile as CCS, but seems to be superior in critical areas like loss in endothelial cell dencity. Furthermore, in one of the main areas where FLACS is said to be inferior (higher rate of posterior capsular rupture) we could not found any significant difference between both methods.

Financial Disclosure:

None