Five year results with the Artiflex myopia phakic intraocular lens: long-term visual function, efficacy, safety and endothelial cell loss

Session Details

Session Title: Refractive
Session Date/Time: Friday 10/02/2017 | 10:30-12:30
Paper Time: 12:00
Venue: Brussels Room 0.4

First Author: S. Jonker THE NETHERLANDS
Co Author(s): A. Ronden   T. Berendschot  I. Saelens  N. Bauer  R. Nuijts     

Abstract Details

Purpose:

Prospective evaluation of visual and refractive parameters, efficacy, safety and endothelial cell loss in a large group of patients five and ten years after implantation with the Artiflex phakic intraocular lens (pIOL) for myopia.

Setting:

Academic Center for Refractive Surgery, University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

Methods:

Data from all myopic patients implanted with the Artiflex pIOL (Ophtec, Groningen, the Netherlands) from 2003 until July 2016 were collected for prospective analysis. Mean preoperative age was 39.6ﾱ10.6. One-hundred-and-sixty-six patients (293 eyes) were implanted, and 133 patients (238 eyes) and 77 patients (146 eyes) completed a follow-up of 1 and 5 years, respectively. Both visual and refractive, topographic and intraocular parameters and endothelial cell density were measured preoperatively, 1 day, 1 week, 1, 3, 6 and 12 months postoperatively, followed by annual visits after completing the first year follow-up.

Results:

Mean logMAR UDVA was 0.004ﾱ0.131 and 0.046ﾱ0.158 logMAR respectively 1 and 5 years postoperatively (p < 0.001). Mean logMAR CDVA was -0.071ﾱ0.097 and -0.052ﾱ0.080 logMAR 1 and 5 years postoperatively (p < 0.001). Mean spherical equivalent (SE) was -0.16ﾱ0.46 D and -0.35ﾱ0.62 D respectively 1 and 5 years postoperatively (p = 0.003). After 1 and 5 years, 96% and 91% of eyes were within 1.0 D of the intended correction. Mean chronic EC loss from 6 months to 5 years postoperatively was -10.7% (p<0.001).

Conclusions:

Over 5 years, both uncorrected and corrected visual acuity showed a minimal but statistically significant (p < 0.001) increase of 0.042 logMAR and 0.021 logMAR, respectively. A similar statistically significant (p = 0.003) but minimal myopisation of -0.18 D was witnessed over 5 years. There was a progressive increased annual endothelial cell loss of -2.38%, which was significantly higher than the expected physiological endothelial cell loss of -0.6% per year.

Financial Disclosure:

None