Study of the macular ganglion cell complex thickness in type 2 diabetes

Session Details

Session Title: Endophthalmitis/ Ocular Infections/ Miscellaneous

Session Date/Time: Tuesday 10/10/2017 | 08:00-10:30

Paper Time: 09:14

Venue: Room 4.6

First Author: : A.Basker INDIA

Co Author(s): :    N. Madhivanan   M. Ariga   M. Palani   P. Nivean   M. Rajan        

Abstract Details

Purpose:

•To evaluate macular ganglion cell complex (GCC) thickness in patients with type 2 diabetes (DM) with or without Diabetic retinopathy (DR) by automated detection on Spectral domain SD – OCT (Optovue) . •To investigate the relationship between GCC thickness and duration of DM , DR status, age and gender

Setting:

This observational study was conducted at MN eye hospital, a tertiary care centre in North Chennai.

Methods:

303 eyes of 212 subjects were examined . All type 2 diabetics with or without DR without macular involvement and no previous Laser treatment were included . Age – gender matched subjects free of ocular or systemic diseases were recruited as controls. DR grading was done based on ETDRS classification. Macular imaging was performed in each eye with SD – OCT . GCC analysis was done, which provided parameters expressed as average and sectoral thickness . To determine the relationship between GCC thickness and duration of DM , DR status, age and gender, multiple linear regression analysis was used.

Results:

Mean GCC thickness at macular was lower in type 2 DM with no DR (87.41 + 13.62 micron; n = 101 ) compared to healthy controls ( 93.60 + 11.45 micron , n = 101). Mean GCC thickness at macular was lower in type 2 DM with DR ( 84.23 + 10.54 micron ,n = 101) when compared to healthy controls and type 2 DM with no DR.

Conclusions:

Objective assessment of GCC finds importance in DR as its evaluation will help in detection of inner retinal loss associated with the disease. Hence, it can be used for early detection of damage and for visual prognosis .

Financial Disclosure:

NONE