Five year results with the Artiflex toric phakic intraocular lens: long-term visual function, efficacy, safety and endothelial cell loss

Session Details

Session Title: Phakic IOLs

Session Date/Time: Monday 09/10/2017 | 08:30-10:20

Paper Time: 08:30

Venue: Meeting Center Room I

First Author: : S.Jonker THE NETHERLANDS

Co Author(s): :    A. Ronden   T. Berendschot   I. Saelens   N. Bauer   R. Nuijts        

Abstract Details

Purpose:

Prospective evaluation of visual and refractive parameters, efficacy, safety and endothelial cell loss in a large group of patients five and ten years after implantation with the Artiflex Toric phakic intraocular lens (pIOL) for astigmatism.

Setting:

Academic Center for Refractive Surgery, University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

Methods:

Data from all myopic patients implanted with the Artiflex Toric pIOL (Ophtec, Groningen, the Netherlands) from 2005 until June 2016 were collected for prospective analysis. Mean preoperative age was 39.6±10.6. One-hundred-and-eleven patients (188 eyes) were implanted, and 85 patients (146 eyes) and 38 patients (64 eyes) completed a follow-up of 1 and 5 years, respectively. Both visual and refractive, topographic and intraocular parameters and endothelial cell density were measured preoperatively, 1 day, 1 week, 1, 3, 6 and 12 months postoperatively, followed by annual visits after completing the first year follow-up.

Results:

Mean logMAR UDVA was 0.035±0.164 and 0.083±0.164 logMAR respectively 1 and 5 years postoperatively (p = 0.002). Mean logMAR CDVA was -0.038±0.120 and -0.025±0.116 logMAR 1 and 5 years postoperatively (p = 0.16). Mean spherical equivalent (SE) was -0.26±0.62 D and -0.40±0.67 D respectively 1 and 5 years postoperatively (p = 0.001). After 1 and 5 years, 96% and 91% of eyes were within 1.0 D of the intended correction. Mean chronic EC loss from 6 months to 5 years postoperatively was -10.2% (p < 0.001).

Conclusions:

Over 5 years, uncorrected visual acuity showed a minimal but statistically significant (p = 0.002) increase of 0.042 logMAR, whereas corrected visual acuity did not show a significant change (p = 0.16). A statistically significant (p = 0.002) myopisation of -0.40 D was witnessed over 5 years, as well as a progressive increased annual endothelial cell loss of -2.26%, which was significantly higher than the expected physiological endothelial cell loss of -0.6% per year.

Financial Disclosure:

NONE