Feasibility of implementing a national corneal transplant registry: 2017 update on the Ottawa pilot study

Session Details

Session Title: Cornea: Surgical I

Session Date/Time: Sunday 08/10/2017 | 10:30-12:30

Paper Time: 12:14

Venue: Meeting Center Room I

First Author: : H.Nithianandan CANADA

Co Author(s): :    P. Morales   Y. Chen   R. Tan   G. Mintsioulis   S. Ziai   K. Baig     

Abstract Details

Purpose:

There are currently only three countries in the world with corneal transplant registries: Australia, Sweden, and India. The purpose of this study was to implement a Canadian Corneal Transplant Registry by conducting an initial pilot study on a smaller scale in the Ottawa region. The objective of the study was to collate information that will help Canadian corneal surgeons improve graft survival and increase transplant success. The 2017 update will review issues and challenges in setting up the registry.

Setting:

The University of Ottawa Eye Institute in Canada.

Methods:

A retrospective medical chart review of all patients who underwent a corneal transplant procedure between 2008 and 2016 at the University of Ottawa Eye Institute was conducted. Details of the donor graft, the procedure itself, indications for the transplantation, visual and surgical outcomes as well as post-operative complications were uploaded onto a de-identified online registry accessible to each participating corneal surgeon.

Results:

Three hundred patients were included in this study. The most prevalent procedures were Descemet’s Stripping Endothelial Keratoplasty/Descemet's Stripping Automated Endothelial Keratoplasty [156/300(52%)] and Penetrating Keratoplasty [93/300 (31%)]. The most common indications for transplantation were Pseudophakic Bullous Keratopathy [72/300 24%)] and Fuch’s Dystrophy [69/300 (23%)]. The most common post-operative complications were elevated intraocular pressure in [63/300 (21%)] of cases and a loose or broken suture in [60/300 (20%)] of cases. The overall incidence of graft failure was [60/300 (20%)]. Rejection and graft detachment led to regrafting in (43/60 (72%)] of the failed grafts.

Conclusions:

We believe that this registry captured the most valuable information for corneal transplant surgeons. This registry will help serve as the framework for a potential large-scale corneal transplant registry in Canada. Future directions for the study include recruiting corneal surgeons across Ontario and ultimately Canada to contribute to the registry.

Financial Disclosure:

NONE