Posters

Isopure: First clinical outcomes of a new extended depth of focus (EDOF) intraocular lens (IOL)

Poster Details

First Author: R.Bilbao Calabuig SPAIN

Co Author(s):    V. Tejerina   F. Gonzalez-López   J. Ortega-Usobiaga   F. Llovet-Osuna           

Abstract Details

Purpose:

To assess first visual outcomes and contrast sensitivity in cataract patients implanted with the ISOPURE (PhysIOL, Liège, Belgium) IOL, a new posterior chamber enhanced monofocal IOL. It is based on the patented ISOFOCAL concept. The optic displays polynomial complex surface design parameters to increase the negative asphericity of the lens optic and thus extend the Depth of Focus compared to standard monofocal IOLs. It is a continuous refractive profile without differentiated zones and without diffractive rings. This enhanced monofocal aspheric optic intraocular lens allows patients to experience high-quality vision at far distances and improves useful vision at intermediate distances.

Setting:

Clinica Baviera, Madrid, Spain.

Methods:

This ongoing prospective case series study included patients with no other ocular comorbidity and corneal astigmatism less than 1.5 diopters that had uneventful cataract surgery and implantation of the Isopure lens. Six months postoperatively monocular and binocular, uncorrected (UDVA) and corrected distance visual acuity (CDVA), uncorrected (UIVA) and distance-corrected intermediate(DCIVA) at 66cm and 80cm and near ( at 40 cm) distance-corrected defocus curves were measured between -2.5D and +1.5D in 0.5 D steps, except for ±0.25 D in order to test for intermediate behaviour of the IOL. Contrast sensitivity was evaluated under mesopic and photopic conditions.

Results:

31 eyes of 20 patients were evaluated. The interim results 3 months postoperatively showed mean spherical equivalent (MRSE) 0.32±0.44D. Mean CDVA, DCIVA (80cm), DCIVA (66cm) in logMAR were -0.02±0.06, 0.17±-0.11 and 0.21±0.12 respectively. Mean UDVA, UIVA (80cm), UIVA (66cm) in logMAR were 0.08±0.14, 0.11±0.13 and 0.14±0.15 respectively. Defocus curves showed a smooth profile along the entire curve, maintaining good visual acuity levels within the intermediate defocus range (up to -1,5D corresponding to 66 cm) following the expected course for an EDOF lens. Photopic and scotopic contrast sensitivity curves were within normal range, similar to those found after monofocal lens implantation.

Conclusions:

Initial clinical results show this enhanced monofocal intraocular lens allows patients to experience excellent far distance vision and provides uncorrected useful vision at intermediate distances without impairing visual quality. This is an important step for an expansion of the monofocal IOL category, as previously most monofocal lenses only corrected for far distances and thus did not improve the intermediate vision that is required for many daily tasks. In the presentation, the definite outcomes after 6 months of follow up will be presented.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented