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An analysis of correlation between monocular parameters and binocular myopia progression in a paediatric group

Poster Details

First Author: S.Bueno Fernández SPAIN

Co Author(s):    A. García del Valle   L. Álvarez-Rementería Capelo   V. Blázquez Sánchez   J. Donís de la Torre   C. Guerra Torralba   C. Navarro Blanco     

Abstract Details

Purpose:

To analyse the validity of using monocular parameters as a sample of binocular myopia progression. To determine the validity weather to use data from one eye or to include data from both eyes in further studies about myopia progression.

Setting:

According to Karakosta, a high correlation between inter-ocular parameters is required to use data from one eye on behalf of both. Sankaridurg, supports including data from both eyes in myopia progression studies (56% had, at least, 0.25D different inter-ocular refraction values, 73% had, at least, 0.10 mm different interocular values).

Methods:

This prospective study included 34 eyes of 17 myopic children (12,7 ± 2,2 years, 55,6% female, 44,4% male) on contact lenses myopic control (peripheral defocus). They were monitored for 18 months. Follow-up examinations every 6 months included subjective refraction (RS), cycloplegic-objective refraction (RO) and axial length measurement (ALX). Axial length was controlled with IOL Master technology.

Results:

Follow-up monocular measurements (ALX, RO, RS) were compared with initial monocular values. Promedial ALX, RS and RO measures between both eyes were also compared to initial promedial values. Based on these data, the Intraclass Correlation Coefficient (ICC) was developed. ICC for monocular data was 0.66 (RO), 0.91 (ALX) and 0.73 (RS). ICC for promedial values was 0.80 (RO), 0.95 (ALX), 0.84 (RS). ICC was moderate to high for the main efficacy variables. ICC was even higher for promedial measurements.

Conclusions:

Although the study was conducted in a small sample, these results suggest that mean data from both eyes can be used without loss of information since the promedial comparison analysis through ICC offer moderate to high correlation values.

Financial Disclosure:

None

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