Posters

Sensitivity of disc morphology, relative afferent pupillary defect, peripapillary retinal nerve fiber layer thickness, and humphrey visual field testing in detecting sellar and parasellar region tumors

Poster Details

First Author: N.Mekhasingharak THAILAND

Co Author(s):    N. Kosaiyaganonth                    

Abstract Details

Purpose:

Compressive optic neuropathy is a cause of optic neuropathy which frequently found in clinical practice. Delay diagnosis can cause irreversible damage of optic nerve. We performed this study to demonstrate the sensitivity of disc morphology, relative afferent pupillary defect (RAPD), peripapillary retinal nerve fiber layer thickness (pRNFL), and Humphrey visual field (VF) testing in detecting sellar and parasellar region tumors.

Setting:

Retrospective study of patients with sellar/parasellar region tumor who presented with visual loss at ophthalmology department of Naresuan university hospital during 1st October 2016 to 31st January 2020

Methods:

All patients with sellar/parasellar region tumor who presented with visual loss at ophthalmology department of Naresuan university hospital during 1st October 2016 to 31st January 2020 were included. All patients underwent ophthalmologic examination, Optical coherence tomography (OCT) imaging, and VF testing. Thinning of the average pRNFL was defined by “outside normal limits” result when compared with a normative database. Bitemporal quadrant/hemianopia and Junctional scotoma VF defects were recognized as positive yield for tumor detection.

Results:

Forty patients were enrolled. Bitemporal quadrant/hemianopia and Junctional scotoma were found as a presenting sign of tumor in 80% (32/40). Optic disc pallor, presence of RAPD, thinning of the average pRNFL were presented in 62.5% (25/40), 75% (30/40), and 55% (22/40) respectively. The sensitivity of VF in detecting tumor was 80%.

Conclusions:

Humphrey visual field testing is the optimal parameter to detect sellar/parasellar region tumor and helpful for requesting the appropriate further investigation.

Financial Disclosure:

None