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Clinical characteristics and treatment outcomes of patients with primary ocular adnexal lymphoma in Thailand

Poster Details

First Author: K.Kanjanarajit THAILAND

Co Author(s):    N. Pokawattana   P. Kruachaipinit                 

Abstract Details

Purpose:

To assess the characteristics and treatment outcomes of patients with primary ocular adnexal lymphoma (POAL) in single tertiary center in Thailand.

Setting:

Retrospective cohort study.

Methods:

Data was collected from electronic medical records and operative notes from Rajavithi Hospital, Bangkok, Thailand between January, 2008 and December, 2019. The clinical characteristics and treatment outcomes were collected and analyzed.

Results:

A total number of 80 patients were identified of which 60% were male. The mean age was 62.94±14.37 years. The most common subtype of lymphoma was extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT) (n= 50, 62.5%). Seventy-six percent of the patients presented with a mass at the ocular adnexa .The sites of origin were as follows: Eyelid (39.7%), lacrimal (32.1%), orbit (16.7%) and conjunctiva (11.5%).The overall response rate was 92% with a complete response rate of 60%. In patients with ocular adnexal lymphoma, the three-year progression-free survival (PFS) were 67.1%.

Conclusions:

Extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT) was the major subtype of POAL in this study. POAL has a high response rate to treatment and excellent survival outcomes.

Financial Disclosure:

None

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