Posters

Anterior-segment optical coherence tomography guided measurement of a melting ulcer for follow-up of corneoscleral thinning progression

Poster Details

First Author: Y.Rotenstreich ISRAEL

Co Author(s):    S. Cohen   Y. Tucker   S. Guttman   E. Bubis   A. Skaat   I. Sher     

Abstract Details

Purpose:

To evaluate the feasibility of using anterior segment optical coherence tomography (AS-OCT) for three-dimensional assessment of corneoscleral thinning progression in ulcers after pterygium removal.

Setting:

University tertiary medical facility.

Methods:

A patient with corneoscleral melting after pterygium removal surgery and mitomycin C treatment was evaluated using AS-OCT at five consecutive time points, up to 2 years. Scans of 8.3X5.6 mm (150X100) containing 41 B-scans spaced 139 µm apart were performed monthly for four months and then at two years following pterygium removal. 10 B-scans of the same position were averaged in a single AS-OCT image. The area of ulcer's section (AUS) was measured in seven fixed landmarks through a horizontally aligned plane in order to provide an estimation of the three-dimensional size of the lesion.

Results:

The AUS in the two superior locations increased during the follow-up period to an average of 114% at two years compared to the initial visit. In the other five locations (three midline and two inferior) the AUS decreased and was on average 64% in the midline and 29% in the inferior locations at 24 months.

Conclusions:

AS-OCT provided a readily available assessment of the lesion's three-dimensional size during repeated follow-ups and identification of localized areas at higher risk for perforation. This method may potentially be useful for corneal surface pathologies requiring repeated follow-ups and may aid in decision-making regarding corneal thickness based on an accurate measurement.

Financial Disclosure:

None