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The results filtration bleb needling in patients with secondary open-angle glaucoma

Poster Details

First Author: T.Savranova UZBEKISTAN

Co Author(s):    V. Rozukulov   S. Saijonov                 

Abstract Details

Purpose:

to study the results of the filtration bleb needling as way of fibrosis prevention in filtration bleb zone after glaucoma surgery in patients with secondary open-angle glaucoma various genesis within a 2-year timefram.

Setting:

A retrospective analysis of glaucoma surgery results was performed in patients with follow-up over 2 years in Republican specialized scientific and practical Medical center of the eye microsurgery, Uzbekistan Tashkent.

Methods:

Mean intraocular pressure (IOP) before the operation was 32.7±0.9 mmHg. Patients age ranged from 25 to 83 years (60,7 ±1,5) Common ocular examinations were conducted that include visometry, perimetry, tonometry, biomicroscopy, gonioscopy, ophthalmoscopy, A-, B- scan, ultrasound biomicroscopy. Antiglaucomatous surgery was performed a trabeculectomy to all patients. All patients were examined on days 1, 7, 15 and 1, 3, 6, 12 and 18 months after the surgery. Needling of the filtration zone depending on the condition of the filtration bleb zone 5-Fluorouracil, Solution of Dexamethasoni – 5% - 0,04 ml were injected to all patients.

Results:

Needling of the filtration bleb was performed to patients after 1 month and removing sutures with type of filtration bleb (according to classification of Yamamoto (1995)). At patients with 2 and 3 type of filtration bleb needling with separation of cystic changed conjunctival adhesions, scleroconjunctival and sclero –scleral adhesions were performed a week after operation then after 2 week and 1 month respectively. In our practice a total number of injections of the 5-Fluorouracil in a poor dilution 0,04 ml to 0,4ml of Solution of Dexamethasoni in a certain cases were reached 6 injections during 6 months after operation. A spilled filtration bleb of the first type were observed in all patients during the examination after 6 month. Hypotensive effect 2 year after the operation was achieved in 100% of cases (40 eyes). IOP of the all patients were stable and at the level of 19±0,1 mmHg.

Conclusions:

patients with secondary open-angle glaucoma recommended dynamic observation of postoperative filtration area with the mandatory procedure of needling at different times after surgery, depending on the severity of the processes of proliferation and degree of rise in IOP. Needling the filtration zone is an effective method of prevention of excessive scarring in the postoperative period in patients with secondary open-angle glaucoma.

Financial Disclosure:

None

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