Posters

Aqueous humour flare in glaucoma patients before and after cataract surgery

Poster Details

First Author: G.Pakuliene LITHUANIA

Co Author(s):    L. Kuzmiene   I. Januleviciene                 

Abstract Details

Purpose:

The purpose of this study was to evaluate aqueous humour flare before and 6 months after cataract surgery in patients with or without open angle glaucoma.

Setting:

The study was carried out in Lithuanian University of Health Sciences Hospital Ophthalmology Clinic. All subjects signed an informed consent form. The study adhered to the principles of Declaration of Helsinki.

Methods:

A prospective case-control study included subjects, who underwent cataract surgery. The open angle glaucoma (OAG) group included subjects with cataract and open angle glaucoma; the control group consisted of subjects with cataract and no other ocular comorbidity. We performed aqueous humour flare measurement (Kowa FM-700 ver. 2.01.200000, Japan) before and 6 months after cataract surgery. Flare count was presented as photon count per millisecond (pc/ms). All of the subjects had compensated intraocular pressure. We estimated the number of different glaucoma medications used by each subject. We performed statistical analysis using SPSS v.23 program package.

Results:

We included 26 subjects in control group and 16 subjects in OAG group. The mean age was similar among groups (p>0.05). The mean(SEM) of aqueous humour flare before cataract surgery was 10.9(1.0) pc/ms in control group and 18.8(2.7) pc/ms in OAG group (p=0.002). Six months after, the mean(SEM) of aqueous humour flare was 12.3(0.76) pc/ms in control group and 18.07(3.2) pc/ms in OAG group (p=0.047). Moderate positive correlation between number of glaucoma medications and aqueous humour flare before cataract surgery (rho = 0.497, p = 0.001) and 6 months after - weak positive correlation (rho = 0.399, p = 0.009).

Conclusions:

The aqueous humour flare was higher in OAG group than in control group before and 6 months after cataract surgery. We found a positive connection between aqueous humour flare and the number of glaucoma medications used. Further studies are needed to evaluate detailed glaucoma medications’ impact on aqueous humour flare.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a competing company