Posters

Successes and failures in a year of Xen 45

Poster Details

First Author: M.Fioretto ITALY

Co Author(s):    M. Andrea Grosso                    

Abstract Details

Purpose:

To report the efficacy of XEN45 implant at 12-month follow-up.


Setting:

Ospedale Santo Spirito di Casale Monferrato (government hospital in Piedmont, Italy)

Methods:

This was a retrospective, non-randomised interventional case series involving patients who underwent XEN45. Primary outcome measures were the intraocular pressure (IOP) and the number of medications at 1-year follow-up visit. Two IOP criteria were chosen to measure success: IOP ≤ 21 mmHg and ≥ 20% reduction from baseline (criteria one); and IOP ≤ 15 mm Hg and ≥ 30% reduction from baseline (criteria two).


Results:

In the overall study population, XEN gel stent significantly reduced intraocular pressure from 24.4 mmHg at baseline to 17.4 mmHg, p < 0.0001. At month 12, 74 (90,24%) eyes were classified as success. The mean number of antiglaucoma medications was significantly reduced in our patients. Obstruction of device 2 eyes (2,4%) , XEN implant extrusion 2 eyes (2,4%), XEN implant intrusion 2 eyes (2,4%), XEN implant extrusion and endophthalmitis1eye (1,2%), good position of device but inadequate intraocular pressure control 1eye (1,2%)

Conclusions:

The XEN45 implant proved to be an effective treatment with a good safety profile at 1-year follow-up period. A strictly follow up of the bleb is mandatory to avoid complications probably due to a low compliance of patients.

Financial Disclosure:

None