Posters

Assessment of post-operative outcomes of combined phacoemulsification and i stent inject on intraocular pressure and anti-glaucoma medication use in patients with glaucoma and ocular hypertension

Poster Details

First Author: Z.Cheng UK

Co Author(s):    M. Macapagal   R. Cheeseman   A. Choudhary              

Abstract Details

Purpose:

To compare the outcomes of combined phacoemulsification and iStent inject on intraocular pressure and anti-glaucoma medication use after 9-12 months in open angles versus narrow angles among patients with glaucoma or ocular hypertension.

Setting:

This is a retrospective cohort study reviewing patients who underwent phacoemulsification with iStent inject surgery at the Royal Liverpool University Hospital from 2018 to 2019.

Methods:

74 out of 99 eyes were included in the study underwent combined phacoemulsification and iStent inject with 9-12 months follow-up. The intraocular pressures, number of anti-glaucoma medications and gonioscopy findings were recorded pre-operatively and post-operative outcomes were analysed. Outcomes of intraocular pressure reduction and medication reduction were compared between patients with open angles and narrow angles. Unpaired T-Test was used to compare intraocular pressure reduction between the two groups.

Results:

Out of the 74 eyes, 62% had open angles, and 38% had narrow angles. At 9-12 months, the narrow-angle group demonstrated a 6.9mmHg decrease in IOP, and the open-angle group 3.8mmHg, which showed statistically significant difference (p value <0.01). No statistically significant difference was found in terms of anti-glaucoma medication use, where the narrow angle group showed an average decrease of anti-glaucoma molecules by 1.6, and the open angle group by 1.4 (p value >0.05). 64% of eyes were medication free at 9-12 months.

Conclusions:

This study shows that the intraocular pressures at 9 to 12 months after combined phacoemulsification with iStent inject are significantly lower in narrow-angle eyes of patients with glaucoma and ocular hypertension than in open-angle eyes. Whilst there is a reduction of anti-glaucoma medication use in both the open-angle and narrow-angle groups, there is no difference between the two groups.

Financial Disclosure:

None