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A study to determine the role of early vitrectomy vs intravitreal antibiotics in patients with postoperative endophthalmitis

Poster Details

First Author: V.Singh INDIA

Co Author(s):    K. Singh   S. Singh   D. Sharma              

Abstract Details

Purpose:

A study to determine the role of early vitrectomy versus intravitreal antibiotic injection in patients with post-operative endophthalmitis

Setting:

The proposed study is conducted at Regional Institute of Ophthalmology (M.D. Eye Hospital, Dr. Katju Road, Nakhas Kona, Prayagraj, India), after taking permission from the ethical committee. A written consent from all the patients was taken.

Methods:

A total of 20 patients who had clinical evidence of endophthalmitis within 6 weeks after cataract surgery were included in the study. Patients were randomized into two groups. In group A (n=7) patients underwent core vitrectomy along with intravitreal antibiotics injection within 48 hours of presentation while in group B (n=13) patients received intavitreal antibiotic injection only.

Results:

In group A (n=7), all the patients has improvement in visual acuity out of them, 5 (71.42%) patients achieved visual acuity of 6/60 or better, while in group B (n=13), 5 (38.46%) patients had improvement in visual acuity, 3 (30.76%) patients did not show any improvement or worsening and 5 (38.46%) patients had worsening of initial visual acuity. The media clarity improved significantly in all the patients of group A (n=7), in which 6 (85.71%) patients achieved the media clarity of grade 1, while in group B (n=13) 6(46.15%) patients achieved media clarity of grade 1 and 2 (15.38%) patients did not have any improvement in media clarity during the follow up periodof 3 months. The complications were more in group B as 2 (15.38%) patients developed retinal detachment, 1 (7.69%) patient had phthisis and 1 (7.69%) patient worsened to panophthalmitis while in group A only 1 (14.28%) patient developed retinal detachment 2 months after the vitrectomy.

Conclusions:

Early vitrectomy when done within 48 hours greatly improves visual acuity and media clarity when compared with intravitreal antibiotics injection alone.

Financial Disclosure:

None

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