Posters

Long-term results of accelerated (30mW/cm2) corneal cross-linking for progressive keratoconus in terms of safety and efficacy

Poster Details

First Author: A.Kirmaci TURKEY

Co Author(s):    Y. Yildirim   G. Yalcinkaya   B. Kepez Yıldız   A. Demirok           

Abstract Details

Purpose:

To evaluate the long-term safety and efficacy of accelerated corneal cross-linking (A-CXL) procedure for the treatment of progressive keratoconus over a minimum 6-year follow-up period.

Setting:

University of Health Sciences Beyoglu Eye Training and Research Hospital, Istanbul, TURKEY

Methods:

The records of keratoconus patients who underwent epithelium-off A-CXL (30 mW/cm² for 4 minutes with a total energy dose of 7.2 J/cm²) in our clinic between the years of 2012 and 2014 were retrospectively reviewed. The clinical characteristics, pre-and-postoperative uncorrected and corrected distance visual acuities (UDVA and CDVA), manifest refraction values, topographical examination results, and corneal aberrations as well as complications were recorded and analyzed.

Results:

Sixty three eyes of 44 patients with mean age of 24.70±4.07 years were included. Thirty two patients completed a minimum 6-years follow-up. The mean CDVA changed from 0.28±0.52 to 0.26±0.58 logMAR; and the mean pachymetry value changed from 466.83±43.57 to 460.72±42.66 microns, postoperatively. At the 6-year follow-up, there was a significant improvement in Kmax (-0.59 D; p=0.025); whereas the change in K1 (-0.25 D; p=0.074) and K2 (-0.17 D; p=0.219) were not statistically significant. No vision-threatening complications occurred. Re-treatment was required in 6 (9.52%) eyes of 4 patients.

Conclusions:

Our results demonstrate that A-CXL is an effective and safe treatment method for progressive keratoconus with stable results over a long-term follow-up.

Financial Disclosure:

None