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Characterization of the severity of paediatric and juvenile keratoconus at the first tomographic diagnosis in a multicentre study

Poster Details

First Author: C.Rocha de Lossada SPAIN

Co Author(s):    J. Sánchez-González   D. Borroni   J. Peraza-Nieves   R. Rachwani   V. Romano   M. Rodríguez-Calvo-de-Mora     

Abstract Details

Purpose:

Characterize paediatric keratoconus patients by analysing tomographic characteristics in the highest paediatric sample, to our knowledge, available in the scientific literature.

Setting:

Regional University Hospital of Malaga (Malaga,Spain); Royal Liverpool University Hospital (Liverpool, England);Tecnolaser Clinic Vision (Seville, Spain), Virgen del Rocío University Hospital (Seville, Spain), Torrecárdenas University Hospital (Almería, Spain) and Monterrey University Hospital Dr. José Eleuterio González (Monterrey, Mexico).

Methods:

Retrospective, cross-sectional, multicentre study. 278 eyes from 139 paediatric patients were evaluated. 104 were males and 35 females. 86 were Caucasian, 23 were Hispanic, 15 Arabian, 3 African and 12 with mixed originFirst diagnosis was prior to 18 years old. KC diagnosis and classification was based on KC Index (≥ 1.07) and Topographic Keratoconus Classification (TKC ≥ 1). Patients were divided in groups, based on age ranges. Statistical analysis was performed with SPSS statistics 25.0. The t student test was performed. ANOVA factor was performed in the three-group comparison.

Results:

230 eyes were diagnosed with paediatric KC. Mean age was 15.48 ± 2.33 (6 to 18) years old. Our results showed how there are differences in terms of TKC (2.08 ± 0.89 and 2.35, P < 0.05), KI (1.20 ± 0.12 and 1.25 ± 0.16, P < 0.05), primary (-1.88 ± 1.39 and -2.40 ± 1.26, P < 0.05) and secondary comma (-0.24 ± 0.40 and -0.37 ± 0.41, P < 0.05) aberration between under 14 years and above 17 years, respectively. Correlation between CDVA and asphericity (r= 0.71, p < 0.01) and spherical aberration (r=0.69, p < 0.01).

Conclusions:

Our findings revealed that keratoconus is aggressive in the paediatric and juvenile population at first diagnosed; thus, we recommend they should be closely monitored and intensively treated. A central paediatric keratoconus has a worse visual prognosis than a paracentral one. Corneal tomography should be systematically performed in children with corneal astigmatism of recent onset.

Financial Disclosure:

None

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