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Influence of topical glaucoma eye drops on corneal curvature and IOL power calculation

Poster Details

First Author: D.Belov RUSSIA

Co Author(s):    V. Nikolaenko                    

Abstract Details

Purpose:

To assess impact of regular application of glaucoma eye drops on corneal curvature and astigmatism in patients preparing for phacoemulsification.

Setting:

Russia, Saint-Petersburg, Multifield Hospital № 2.

Methods:

In total 478 patients preparing for phacoemulsification (478 eyes) divided in 3 groups: 1st group: glaucoma patients on treatment by topical eye drops (№ 198); 2nd group: patients without concomitant pathology (№ 249); 3rd group: glaucoma patients after trabeculectomy without local topical eye drops (№ 31). For each patient keratometry was performed by IOL-Master 500. Mean keratometry and corneal astigmatism values were compared between groups. 1 month after phacoemulsification IOL power calculation error was assessed in study groups. Barrett Univesal II formula was used to IOL calculation in all cases.

Results:

There was mild (0.5 D) but statistically significant differens between 1st and 2nd groups in corneal power (44.4±1.82 versus 43.9±2.0 D respectively, p=0,022). Nevertheless, there was no significant difference in corneal curvature in patients with previous trabeculectomy (44.1±1.59 D). Any difference in corneal astigmatism level among study groups was no found (0.82±0.61 D, 0.61±2.63 D and 0.81±0.54 D for groups respectevely). Mean IOL power calculation error was comparable for groups: -0,08±0,59 D, -0.06±0.56 D and +0.003±0.61 D for study groups.

Conclusions:

High requirements for cataract surgery in the modern world require an accurate assessment of the biometric parameters for precise IOL calculation. Instability of the tear film in patients with dry eye disease (DED) can lead to corneal curvature fluctuations. Almost all glaucoma patients receiving daily instillations of eye drops suffer from DED. There was mild (0,5D) but significant differense between 1st and 2nd groups in corneal power (44.4±1.82 versus 43.9±2.0 D). Probably It means that corneal curvature strive to increase in patients with DED.

Financial Disclosure:

None

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